2’-β-C-Methyl-3-deazauri dine

Names

[ Name ]:
2’-β-C-Methyl-3-deazauri dine

[Synonym ]:
2(1H)-Pyridinone, 4-hydroxy-1-(2-C-methyl-β-D-ribofuranosyl)-
4-Hydroxy-1-(2-C-methyl-β-D-ribofuranosyl)-2(1H)-pyridinone

Biological Activity

[Description]:

2’-β-C-Methyl-3-deazauri dine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
544.6±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₅NO₆

[ Molecular Weight ]:
257.24

[ Flash Point ]:
283.2±30.1 °C

[ Exact Mass ]:
257.089935

[ LogP ]:
-0.47

[ Vapour Pressure ]:
0.0±3.3 mmHg at 25°C

[ Index of Refraction ]:
1.669

2’-β-C-Methyl-3-deazauri dine

Names

Biological Activity

Chemical & Physical Properties

Related Compounds