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2-Furancarboxaldehyde,5-nitro-, oxime, [C(Z)]-

Names

[ CAS No. ]:
6236-05-1

[ Name ]:
2-Furancarboxaldehyde,5-nitro-, oxime, [C(Z)]-

[Synonym ]:
5-Nitro-furfural-(Z)-oxim
5-Nitro-2-furancarboxaldehyde oxime,anti-5-Nitro-2-furaldoxime
5-nitro-furfural-(Z)-oxime
ANTI-5-NITRO-2-FURALDOXIME
nitrofuroxime
cis-5-nitrofuran-2-aldoxime
NIFUROSSIMA
5-Nitro-2-furancarbaldehyde (Z)-oxime
anti-5-Nitro-furfural-oxim

Biological Activity

[Description]:

Nifuroxime is an anti-infective agent. Nifuroxime can be used in the research of fungal infections[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal

[In Vitro]

Nifuroxime (10 μg/mL) inhibits mycelial growth[1]. Nifuroxime (0.5 mM, 20 min) effectively sensitize hypoxic cells to ionizing radiation in a tumour-like environment[2].

Chemical & Physical Properties

[ Density]:
1.58g/cm3

[ Boiling Point ]:
274.8ºC at 760 mmHg

[ Melting Point ]:
160-163ºC

[ Molecular Formula ]:
C5H4N2O4

[ Molecular Weight ]:
156.09600

[ Flash Point ]:
120ºC

[ Exact Mass ]:
156.01700

[ PSA ]:
91.55000

[ LogP ]:
1.51910

[ Index of Refraction ]:
1.608

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LT7527000
CHEMICAL NAME :
2-Furaldehyde, 5-nitro-, oxime, (Z)- (8CI)
CAS REGISTRY NUMBER :
6236-05-1
LAST UPDATED :
199410
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C5-H4-N2-O4
MOLECULAR WEIGHT :
156.11

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
100 mg/L
REFERENCE :
BJCSB5 British Journal of Cancer, Supplement. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2ZS, UK) No.1- 1973- Volume(issue)/page/year: 3,124,1978

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds