Tubulin polymerization-IN-29

Names

[ CAS No. ]:
630058-59-2

[ Name ]:
Tubulin polymerization-IN-29

Biological Activity

[Description]:

Tubulin polymerization-IN-29 (compound 6g) is a potent tubulin polymerization inhibitor. Tubulin polymerization-IN-29 exhibits potent antiproliferative activity. Tubulin polymerization-IN-29 can induce HeLa cells arrest in G2/M phase[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin
Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin

[References]

[1]. Li Q, et, al. Synthesis and biological evaluation of benzofuran-based 3,4,5-trimethoxybenzamide derivatives as novel tubulin polymerization inhibitors. Bioorg Chem. 2020 Sep;102:104076.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H20FNO6

[ Molecular Weight ]:
449.43

Related Compounds