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Uridine-5-oxyacetic acid methyl ester

Names

[ CAS No. ]:
66536-81-0

[ Name ]:
Uridine-5-oxyacetic acid methyl ester

[Synonym ]:
Methyluridine-5-oxyacetic acid
methyl 2-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]oxyacetate
5-(2-methoxy-2-oxoethoxy)uridine
uridine-5-oxyacetic acid-methylester
5-methoxycarbonylmethoxyuridine

Biological Activity

[Description]:

Uridine 5-oxyacetic acid methyl ester is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C12H16N2O9

[ Molecular Weight ]:
332.26

[ Exact Mass ]:
332.08600

[ PSA ]:
160.57000


Related Compounds