N6,N6-Dimethyl-xylo-adenosine

Names

[ CAS No. ]:
669055-52-1

[ Name ]:
N6,N6-Dimethyl-xylo-adenosine

[Synonym ]:
(1R)-1-(6-dimethylamino-purin-9-yl)-D-1,4-anhydro-xylitol
(1R)-1-(6-Dimethylamino-purin-9-yl)-D-1,4-anhydro-xylit

Biological Activity

[Description]:

N6,N6-Dimethyl-xylo-adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

[2]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

Chemical & Physical Properties

[ Molecular Formula ]:
C12H17N5O4

[ Molecular Weight ]:
295.29

[ Exact Mass ]:
295.12800

[ PSA ]:
116.76000

Precursor & DownStream

Precursor

DownStream

Related Compounds