5'-Deoxy-5'-iodoguanosine

Names

[ Name ]:
5'-Deoxy-5'-iodoguanosine

[Synonym ]:
5'-iodo-5'-deoxy-guanosine
5'-DEOXY-5'-IODOGUANOSINE
5'-Deoxy-5'-jodguanosin
2-amino-9-((2R,3R,4S,5S)-3,4-dihydroxy-5-(iodomethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one
2-amino-9-((2R,3R,4S,5S)-3,4-dihydroxy-5-(iodomethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one
5'-IODO-5'-DEOXYGUANOSINE
5'-deoxy-5'-iodoguanisine

Biological Activity

[Description]:

5'-Deoxy-5'-iodoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁H₁₅N₅O₄

[ Molecular Weight ]:
281.27

[ Exact Mass ]:
392.99300

[ PSA ]:
139.28000

[ Storage condition ]:
2-8°C

5'-Deoxy-5'-iodoguanosine

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds