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2',5-difluoro-2'-deoxy-1-arabinosyluracil

Names

[ CAS No. ]:
69123-95-1

[ Name ]:
2',5-difluoro-2'-deoxy-1-arabinosyluracil

[Synonym ]:
2',5-difluoro-2'-deoxy-1-arabinosyluracil
Iron 2-ethylhexanoate
2-Ethylhexanoic acid,iron salt
Ferric ferrous 2-ethylhexanoate

Biological Activity

[Description]:

5-Fluoro-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (2',5-difluoro-2'-deoxy-1-arabinosyluracil) is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.  

Chemical & Physical Properties

[ Density]:
1.69 g/cm3

[ Molecular Formula ]:
C10H14F2N2O5

[ Molecular Weight ]:
280.23

[ Exact Mass ]:
176.17800

[ PSA ]:
37.30000

[ LogP ]:
3.55960

[ Index of Refraction ]:
1.582

Related Compounds