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Thymidine,3',5'-diacetate

Names

[ CAS No. ]:
6979-97-1

[ Name ]:
Thymidine,3',5'-diacetate

[Synonym ]:
1'(2'-DEOXY-3',5'-DI-O-ACETYL-
Thymidine,3',5'-diacetate
2'-deoxy-3',5'-di-O-acetylthymidine
EINECS 230-244-5
DIACETYL THYMIDINE
3',5'-di-O-acetyl-2'-desoxythymidine

Biological Activity

[Description]:

3’,5’-Di-O-acetylthymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
1.37 g/cm3

[ Melting Point ]:
126 - 128ºC

[ Molecular Formula ]:
C14H18N2O7

[ Molecular Weight ]:
326.30

[ Exact Mass ]:
326.11100

[ PSA ]:
116.69000

[ Index of Refraction ]:
1.549

MSDS

Click to get detail MSDS

Safety Information

[ Safety Phrases ]:
S28-S37-S45-S24/25

Precursor & DownStream

Precursor

DownStream

Related Compounds