2-(4-Methoxyphenyl)ethanol

Names

[ CAS No. ]:
702-23-8

[ Name ]:
2-(4-Methoxyphenyl)ethanol

[Synonym ]:
MFCD00002900
EINECS 211-866-6
2-(4-Methoxyphenyl)ethanol
2-(p-Methoxyphenyl)ethyl alcohol
Benzeneethanol, 4-methoxy-

Biological Activity

[Description]:

4-Methoxyphenethyl alcohol, an aromatic alcohol, is the major component in the anise-like odour produced by A. albispathus Hett. 4-Methoxyphenethyl alcohol can inhibits the protein, RNA and DNA synthesis in Escherichia coli[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

[References]

[1]. Kite GC, et, al. Inflorescence odours of Amorphophallus and Pseudodracontium (Araceae). Phytochemistry. 1997 Sep; 46(1): 71-75.

[2]. Kite GC, et, al. Inflorescence odours of Amorphophallus and Pseudodracontium (Araceae). Phytochemistry. 1997 Sep; 46(1): 71-75.

[3]. Khafagy EZ, et, al. Inhibition of protein, RNA and DNA synthesis in Escherichia coli by p-methoxyphenethyl alcohol. Biochim Biophys Acta. 1966 Sep;123(3):646-8.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
257.5±15.0 °C at 760 mmHg

[ Melting Point ]:
26-28 °C(lit.)

[ Molecular Formula ]:
C₉H₁₂O₂

[ Molecular Weight ]:
152.190

[ Flash Point ]:
110.2±14.6 °C

[ Exact Mass ]:
152.083725

[ PSA ]:
29.46000

[ LogP ]:
1.27

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.524

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

An asymmetric catalytic carbon? carbon bond formation in a fluorous biphasic system based on perfluoroalkyl-BINOL. Tian Y and Chan KS.

Tetrahedron Lett. 41(45) , 8813-8816, (2000)

Biocatalytic anti-Prelog stereoselective reduction of 4'-methoxyacetophenone to (R)-1-(4-methoxyphenyl) ethanol with immobilized Trigonopsis variabilis AS2. 1611 cells using an ionic liquid-containing medium. Lou W-Y, et al.

Green Chem. 11(9) , 1377-1384, (2009)

Synthesis of 5-(ω-sulfhydrylalkyl) salicylaldehydes as precursors for the preparation of alkanethiol-modified metal salens. Ji C and Peters DG

Tetrahedron Lett. 42(35) , 6065-6067, (2001)