Methyl 6-amino-9-β-D-ribofuranosyl-9H-purine-2-carboxylate

Names

[ Name ]:
Methyl 6-amino-9-β-D-ribofuranosyl-9H-purine-2-carboxylate

Biological Activity

[Description]:

Methyl 6-amino-9-β-D-ribofuranosyl-9H-purine-2-carboxylate is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₁₅N₅O₆

[ Molecular Weight ]:
325.28