CP-775146

Names

[ Name ]:
CP-775146

[Synonym ]:
(S)-2-(3-{1-[(4-isopropylphenyl)acetyl]piperidin-3-yl}phenoxy)-2-methylpropionic acid
(S)-2-(3-(1-(2-(4-isopropylphenyl)acetyl)piperidin-3-yl)phenoxy)-2-methylpropanoic acid

Biological Activity

[Description]:

CP-775146 is a selective PPARα agonist that binds strongly to the PPARα ligand. CP-775146 efficiently alleviates obesity-induced liver damage, prevents lipid accumulation by activating the liver fatty acid β-oxidation pathway[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR

Research Areas >> Metabolic Disease

[References]

[1]. Shengjie Tang, et al. The Effects of New Selective PPAR α Agonist CP775146 on Systematic Lipid Metabolism in Obese Mice and Its Potential Mechanism. J Diabetes Res. 2020 May 4;2020:4179852.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₃₃NO₄

[ Molecular Weight ]:
423.54500

[ Exact Mass ]:
423.24100

[ PSA ]:
66.84000

[ LogP ]:
4.93860

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H410

[ Precautionary Statements ]:
P273-P501

[ RIDADR ]:
UN 3077 9 / PGIII