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3’-Amino-3’-deoxycytidine

Names

[ CAS No. ]:
70580-89-1

[ Name ]:
3’-Amino-3’-deoxycytidine

[Synonym ]:
Cytidine, 3'-amino-3'-deoxy-
3'-Amino-3'-deoxycytidine

Biological Activity

[Description]:

3’-Amino-3’-deoxycytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
531.3±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C9H14N4O4

[ Molecular Weight ]:
242.23

[ Flash Point ]:
275.1±32.9 °C

[ Exact Mass ]:
242.101501

[ LogP ]:
-1.83

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.781

Related Compounds