Adenosine,5'-azido-5'-deoxy-

Names

[ CAS No. ]:
737-76-8

[ Name ]:
Adenosine,5'-azido-5'-deoxy-

[Synonym ]:
5'-Azido-5'-desoxy-adenosin
5'-azido-5'-deoxyAdo
5'-Deoxy-5'-azido-adenosin
5'-Deoxy-5'-azidoadenosine
5'-Azidoadenosine
5'-azido-5'-deoxyadenosine

Biological Activity

[Description]:

5′-Azido-5′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₁₂N₈O₃

[ Molecular Weight ]:
292.25

[ Exact Mass ]:
292.10300

[ PSA ]:
169.06000

Adenosine,5'-azido-5'-deoxy-

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds