2'-Deoxy-2'-fluoro-D-inosine

Names

[ Name ]:
2'-Deoxy-2'-fluoro-D-inosine

[Synonym ]:
2'-Deoxy-2'-fluoroinosine
2'-FLUORO-2'-DEOXYINOSINE
Inosine,2'-deoxy-2'-fluoro
2'-Dfin
2'-Deoxy-2'-fluoro-D-inosine
2'-F-2'-dI

Biological Activity

[Description]:

2’-Deoxy-2’-fluoroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
2.01g/cm3

[ Boiling Point ]:
682.1ºC at 760mmHg

[ Molecular Formula ]:
C₁₀H₁₁FN₄O₄

[ Molecular Weight ]:
270.22

[ Flash Point ]:
366.3ºC

[ Exact Mass ]:
270.07600

[ PSA ]:
113.26000

[ Index of Refraction ]:
1.809

Safety Information

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%