5’-O-(4,4’-Dimethoxytrityl)-2’-O-t-butyldimethylsilyl adenosine

Names

[ Name ]:
5’-O-(4,4’-Dimethoxytrityl)-2’-O-t-butyldimethylsilyl adenosine

[Synonym ]:
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine

Biological Activity

[Description]:

5’-O-(4,4’-Dimethoxytrityl)-2’-O-t-butyldimethylsilyl adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₇H₄₅N₅O₆Si

[ Molecular Weight ]:
683.87

[ Exact Mass ]:
683.31400

[ PSA ]:
136.00000

[ LogP ]:
6.66430

5’-O-(4,4’-Dimethoxytrityl)-2’-O-t-butyldimethylsilyl adenosine

Names

Biological Activity

Chemical & Physical Properties

Related Compounds