3’-Deoxy-3’-α-C-methyl-5-methyluridine

Names

[ CAS No. ]:
847650-50-4

[ Name ]:
3’-Deoxy-3’-α-C-methyl-5-methyluridine

[Synonym ]:
3'-Deoxy-3',5-dimethyluridine
Uridine, 3'-deoxy-3',5-dimethyl-

Biological Activity

[Description]:

3’-Deoxy-3’-α-C-methyl-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C11H16N2O5

[ Molecular Weight ]:
256.26

[ Exact Mass ]:
256.105927

[ LogP ]:
-0.67

[ Index of Refraction ]:
1.562

Related Compounds