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6-aminoallopurinol riboside

Names

[ CAS No. ]:
85426-74-0

[ Name ]:
6-aminoallopurinol riboside

[Synonym ]:
7-Deaza-8-azaguanosine
6-Aminoallopurinol riboside

Biological Activity

[Description]:

8-Aza-7-deazguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C10H13N5O5

[ Molecular Weight ]:
283.24

[ Exact Mass ]:
283.09200

[ PSA ]:
160.50000

Related Compounds