RSV-IN-4

Names

[ CAS No. ]:
862825-89-6

[ Name ]:
RSV-IN-4

Biological Activity

[Description]:

RSV-IN-4 (Compound 2) is a dual inhibitor of respiratory syncytial virus (RSV) and influenza virus A (IAV). RSV-IN-4 shows anti-RSV activity (EC50 = 11.76 μM)[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus
Research Areas >> Infection
Signaling Pathways >> Anti-infection >> RSV

[In Vitro]

RSV-IN-4 (compound 2) (50 µM)shows the inhibition of 83.24% for RSV in a fluorescence-based assay with little or no toxicity to HEp-2 cells[1].

[References]

[1]. Guo-Ning Zhang, et al. Design and synthesis of 2-((1H-indol-3-yl)thio)-N-phenyl-acetamides as novel dual inhibitors of respiratory syncytial virus and influenza virus A. Eur J Med Chem. 2020 Jan 15;186:111861.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H18N2O2S

[ Molecular Weight ]:
326.41

Related Compounds