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Ganoderic acid X

Names

[ CAS No. ]:
86377-53-9

[ Name ]:
Ganoderic acid X

[Synonym ]:
(3α,15α,24E)-15-Acetoxy-3-hydroxylanosta-7,9(11),24-trien-26-oic acid
Lanosta-7,9(11),24-trien-26-oic acid, 15-(acetyloxy)-3-hydroxy-, (3α,15α,24E)-

Biological Activity

[Description]:

Ganoderic acid X is a lanostanoid triterpene that can be extracted from Ganoderma amboinense. Ganoderic acid X inhibits topoisomerases and induces Apoptosis of cancer cells[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase

[References]

[1]. Li CH, et al. Ganoderic acid X, a lanostanoid triterpene, inhibits topoisomerases and induces apoptosis of cancer cells. Life Sci. 2005 Jun 3;77(3):252-65.  

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
625.5±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C32H48O5

[ Molecular Weight ]:
512.721

[ Flash Point ]:
193.1±25.0 °C

[ Exact Mass ]:
512.350159

[ LogP ]:
7.87

[ Vapour Pressure ]:
0.0±4.1 mmHg at 25°C

[ Index of Refraction ]:
1.555

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds