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Sequosempervirin B

Names

[ CAS No. ]:
864719-17-5

[ Name ]:
Sequosempervirin B

[Synonym ]:
(2S,3S,4E)-3-(4-Hydroxy-3-methoxyphenyl)-5-(4-hydroxyphenyl)-4-pentene-1,2-diol
4-Pentene-1,2-diol, 3-(4-hydroxy-3-methoxyphenyl)-5-(4-hydroxyphenyl)-, (2S,3S,4E)-

Biological Activity

[Description]:

Sequosempervirin B, a norlignan isolated from the branches and leaves of Sequoia sempervirens, has antifungal properties. Sequosempervirin B has an inhibitory effect on cyclic AMP phosphodiesterase[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)
Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Zhang YM, et al. Norlignans from Sequoia sempervirens. Chem Biodivers. 2005 Apr;2(4):497-505.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
589.0±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H20O5

[ Molecular Weight ]:
316.35

[ Flash Point ]:
310.0±30.1 °C

[ Exact Mass ]:
316.131073

[ PSA ]:
90.15000

[ LogP ]:
0.94

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.663

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds