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Eg5 Inhibitor V, trans-24

Names

[ CAS No. ]:
869304-55-2

[ Name ]:
Eg5 Inhibitor V, trans-24

[Synonym ]:
Eg5 Inhibitor V,trans-24

Biological Activity

[Description]:

Eg5 Inhibitor V, trans-24 is a potent and specific Eg5 inhibitor with an IC50 of 0.65 μM, and can be used in the research of cancer.

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Kinesin
Signaling Pathways >> Cytoskeleton >> Kinesin
Research Areas >> Cancer

[Target]

Eg5:0.65 μM (IC50)


[In Vitro]

Eg5 Inhibitor V, trans-24 is a potent and specific Eg5 inhibitor with an IC50 of 0.65 μM, and can be used in the research of cancer[1].

[References]

[1]. Sunder-Plassmann N, et al. Synthesis and biological evaluation of new tetrahydro-beta-carbolines as inhibitors of the mitotic kinesin Eg5. Bioorg Med Chem. 2005 Nov 15;13(22):6094-111.


[Related Small Molecules]

ARRY-520 | GSK-923295 | Ispinesib | Kif15-IN-1 | Monastrol | Kif15-IN-2 | Litronesib | CW-069 | K 858 | SB743921 | AZ82 | EMD534085 | Paprotrain

Chemical & Physical Properties

[ Molecular Formula ]:
C26H21N3O3

[ Molecular Weight ]:
423.46300

[ Exact Mass ]:
423.15800

[ PSA ]:
76.64000

[ LogP ]:
4.22780

Related Compounds