<Suppliers Price>

Sirt2-IN-5

Names

[ CAS No. ]:
902456-47-7

[ Name ]:
Sirt2-IN-5

Biological Activity

[Description]:

Sirt2-IN-5 is a potent SIRT2 inhibtor[1].

[Related Catalog]:

Signaling Pathways >> Epigenetics >> Sirtuin

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin

Research Areas >> Neurological Disease

[Target]

SIRT2

[In Vitro]

Sirt2-IN-5 shows 47.95% SIRT2 inhibition at 100 µM[1].

[References]

[1]. Sukuroglu, M.K., et al. The potential of 4-aryl-6-morpholino-3(2H)-pyridazinone-2-arylpiperazinylacetamide as a new scaffold for SIRT2 inhibition: in silico approach guided by pharmacophore mapping and molecular docking. Med Chem Res 30, 1915–1924 (2021).

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₂₇Cl₂N₅O₃

[ Molecular Weight ]:
528.43

Related Compounds