ec 3.3.1.1

Names

[ Name ]:
ec 3.3.1.1

[Synonym ]:
Adenosylhomocysteine hydrolase
E.C. 3.3.1.1
S-Adenosyl-L-homocysteine hydrolase
S-Adenosylhomocysteinase
S-Adenosylhomocysteine hydrolase
S-Adenosylhomocysteine synthase
SAH hydrolase

Biological Activity

[Description]:

Adenosylhomocysteinase (SAHH; AHCY) is a highly conserved enzyme. Adenosylhomocysteinase reversible catalyzes S-adenosylhomocysteine (SAH) to adenosine and L-homocysteine. The serum exosomal Adenosylhomocysteinase level can be used as a prognostic biomarker in HBV-LC patients[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> HBV

Research Areas >> Metabolic Disease

[References]

[1]. Tong L, et al. Prognostic Value of Serum Exosomal AHCY Expression in Hepatitis B-Induced Liver Cirrhosis. Front Med (Lausanne). 2021 Nov 8;8:777452.

[2]. Vizán P, Di Croce L, Aranda S. Functional and Pathological Roles of AHCY. Front Cell Dev Biol. 2021 Mar 31;9:654344.

Chemical & Physical Properties

[ Appearance of Characters ]:
buffered aqueous glycerol solution

[ Storage condition ]:
−70°C

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
35079090

Articles

Initial characterization of the human central proteome.

BMC Syst. Biol. 5 , 17, (2011)

On the basis of large proteomics datasets measured from seven human cell lines we consider their intersection as an approximation of the human central proteome, which is the set of proteins ubiquitous...

A quantitative atlas of mitotic phosphorylation.

Proc. Natl. Acad. Sci. U. S. A. 105(31) , 10762-7, (2008)

The eukaryotic cell division cycle is characterized by a sequence of orderly and highly regulated events resulting in the duplication and separation of all cellular material into two newly formed daug...

Complete sequencing and characterization of 21,243 full-length human cDNAs.

Nat. Genet. 36 , 40-5, (2004)

As a base for human transcriptome and functional genomics, we created the "full-length long Japan" (FLJ) collection of sequenced human cDNAs. We determined the entire sequence of 21,243 selected clone...