Palmitic acid-d5

Names

[ CAS No. ]:
1219802-61-5

[ Name ]:
Palmitic acid-d5

[Synonym ]:
n-hexadecanoic acid
1-hexadecanoic acid
hexdecanoic acid
Hexadecanoic acid
Neo-Fat 16
Palmitic acid

Biological Activity

[Description]:

Palmitic acid-d5 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> HSP
Signaling Pathways >> Cell Cycle/DNA Damage >> HSP

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Harada H, et al. Antitumor activity of palmitic acid found as a selective cytotoxic substance in a marine red alga. Anticancer Res. 2002 Sep-Oct;22(5):2587-90.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
340.6±5.0 °C at 760 mmHg

[ Molecular Formula ]:
C16H27D5O2

[ Molecular Weight ]:
261.45

[ Flash Point ]:
154.1±12.5 °C

[ Exact Mass ]:
256.240234

[ LogP ]:
7.15

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.454

Related Compounds