2-Amino-N,N-dimethyl-2′-C-methyladenosine

Names

[ CAS No. ]:
1336975-57-5

[ Name ]:
2-Amino-N,N-dimethyl-2′-C-methyladenosine

[Synonym ]:
2-Amino-N,N-dimethyl-2'-C-methyladenosine
Adenosine, 2-amino-N,N-dimethyl-2'-C-methyl-

Biological Activity

[Description]:

2-Amino-N,N-dimethyl-2′-C-methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
684.3±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C13H20N6O4

[ Molecular Weight ]:
324.34

[ Flash Point ]:
367.6±34.3 °C

[ Exact Mass ]:
324.154602

[ LogP ]:
1.08

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.754

Related Compounds