2’-Fluoro-2-thio-2’-dU-3’-phosphoramidite

Names

[ CAS No. ]:
152753-94-1

[ Name ]:
2’-Fluoro-2-thio-2’-dU-3’-phosphoramidite

Biological Activity

[Description]:

2’-Fluoro-2-thio-2’-dU-3’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds