Chitin synthase inhibitor 3

Names

[ CAS No. ]:
2416338-26-4

[ Name ]:
Chitin synthase inhibitor 3

Biological Activity

[Description]:

Chitin synthase inhibitor 3 (compound 2d) is a potent chitin synthase inhibitor with an IC50 value of 0.16 mM, and MIC of 1 µg/mL against candida albicans. Antifungal activity[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal

[Target]

IC50: 0.16 mM (chitin synthase)[1] MIC: 1 µg/mL in candida albicans[1]


[References]

[1]. Li B, et al. Design, synthesis and biological evaluation of novel 3,4-dihydro-2(1H)-quinolinone derivatives as potential chitin synthase inhibitors and antifungal agents. Eur J Med Chem. 2020 Jun 1;195:112278.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H19N3O4

[ Molecular Weight ]:
365.38

Related Compounds