Gemcitabine-13C,15N2 hydrochloride
Names
[ CAS No. ]:
2757566-59-7
[ Name ]:
Gemcitabine-13C,15N2 hydrochloride
Biological Activity
[Description]:
Gemcitabine-13C,15N2 (hydrochloride) is the 13C and 15N labeled Gemcitabine hydrochloride[1]. Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis[2][3].
[Related Catalog]:
[In Vitro]
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C813CH12ClF2N15N2O4
[ Molecular Weight ]:
302.64