5-Hydroxymethyl-arauridine

Names

[ CAS No. ]:
28608-82-4

[ Name ]:
5-Hydroxymethyl-arauridine

[Synonym ]:
2,4(1H,3H)-Pyrimidinedione, 1-β-D-arabinofuranosyl-5-(hydroxymethyl)-
1-(β-D-Arabinofuranosyl)-5-(hydroxymethyl)-2,4(1H,3H)-pyrimidinedione

Biological Activity

[Description]:

5-Hydroxymethyl-arauridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.  

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Molecular Formula ]:
C10H14N2O7

[ Molecular Weight ]:
274.23

[ Exact Mass ]:
274.080109

[ LogP ]:
-1.40

[ Index of Refraction ]:
1.646

Related Compounds