3′-Deoxy-3′-methylcytidine

Names

[ Name ]:
3′-Deoxy-3′-methylcytidine

[Synonym ]:
Cytidine, 3'-deoxy-3'-methyl-
3'-Deoxy-3'-methylcytidine

Biological Activity

[Description]:

3′-Deoxy-3′-methylcytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
487.2±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₅N₃O₄

[ Molecular Weight ]:
241.24

[ Flash Point ]:
248.4±31.5 °C

[ Exact Mass ]:
241.106262

[ LogP ]:
-1.21

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.694