2’-Deoxy-N4,N4-dimethylcytidine

Names

[ Name ]:
2’-Deoxy-N4,N4-dimethylcytidine

[Synonym ]:
Cytidine, 2'-deoxy-N,N-dimethyl-
2'-Deoxy-N,N-dimethylcytidine

Biological Activity

[Description]:

2’-Deoxy-N4,N4-dimethylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
453.4±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₇N₃O₄

[ Molecular Weight ]:
255.27

[ Flash Point ]:
228.0±31.5 °C

[ Exact Mass ]:
255.121902

[ LogP ]:
-1.58

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.632