Magnolol
Names
[ CAS No. ]:
528-43-8
[ Name ]:
Magnolol
[Synonym ]:
[1,1'-Biphenyl]-2,2'-diol, 5,5'-di-2-propen-1-yl-
MAGNOLIABARKEXTRACT
DEHYDRODICHAVICOL
Honokiol std.
5,5'-Diallyl-2,2'-biphenyldiol
Magnolol
[1,1'-Biphenyl]-2,2'-diol, 5,5'-di-2-propenyl-
1U2R DQ CR BQ E2U1
MFCD00016658
2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphenol
2,2'-Bichavicol
5,5'-Diallyl-[1,1'-biphenyl]-2,2'-diol
5,5'-Diallyl-2,2'-dihydroxybiphenyl
5,5′-Diallyl-2,2′-biphenyldiol
Maglol
5,5'-diallyl-biphenyl-2,2'-diol
2,2'-Dihydroxy-5,5'-diallylbiphenyl
5,5'-Diallylbiphenyl-2,2'-diol
5,5'-Di-2-propenyl-[1,1'-biphenyl]-2,2'-diol
5,5'-Di(2-propèn-1-yl)-2,2'-biphényldiol
Biological Activity
[Description]:
[Related Catalog]:
[Target]
RXRα:10.4 μM (EC50)
PPARγ:17.7 μM (EC50)
[In Vitro]
[In Vivo]
[Kinase Assay]
[Cell Assay]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
401.0±40.0 °C at 760 mmHg
[ Melting Point ]:
99 - 101ºC
[ Molecular Formula ]:
C18H18O2
[ Molecular Weight ]:
266.334
[ Flash Point ]:
184.5±21.9 °C
[ Exact Mass ]:
266.130676
[ PSA ]:
40.46000
[ LogP ]:
3.94
[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C
[ Index of Refraction ]:
1.602
[ Storage condition ]:
2-8°C
MSDS
Safety Information
[ Symbol ]:
GHS05, GHS07, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H315-H318-H335-H411
[ Precautionary Statements ]:
P261-P273-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
N:Dangerousfortheenvironment;
[ Risk Phrases ]:
R37/38;R41;R51/53
[ Safety Phrases ]:
S26-S39-S61
[ RIDADR ]:
UN 3077
[ RTECS ]:
DV5105500
[ Hazard Class ]:
9.0
[ HS Code ]:
2907299090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2907299090
[ Summary ]:
2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%
Articles
J. Pharm. Sci. 104 , 2369-77, (2015)
In this study, we aimed to determine the glucuronidation potential of psoralidin in humans and to perform validation on use of psoralidin-3-O-glucuronidation as a functional marker for UGT1A9. Glucuro...
Resuscitation from experimental traumatic brain injury by magnolol therapy.J. Surg. Res. 184(2) , 1045-52, (2013)
The purpose of the present study was to determine whether magnolol, a free radical scavenger, mitigates the deleterious effects of traumatic brain injury (TBI).Traumatic brain injuries were induced in...
Magnolol inhibits growth of gallbladder cancer cells through the p53 pathway.Cancer Sci. 106 , 1341-50, (2015)
Magnolol, the major active compound found in Magnolia officinalis has a wide range of clinical applications due to its anti-inflammation and anti-oxidation effects. This study investigated the effects...