2′-Deoxy-2-hydrazinyladenosine

Names

[ CAS No. ]:
1000296-26-3

[ Name ]:
2′-Deoxy-2-hydrazinyladenosine

[Synonym ]:
(2R,3S,5R)-5-(6-Amino-2-hydrazino-purin-9-yl)-2-hydroxymethyl-tetrahydro-furan-3-ol

Biological Activity

[Description]:

2′-Deoxy-2-hydrazinyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C10H15N7O3

[ Molecular Weight ]:
281.27

[ Exact Mass ]:
281.12400

[ PSA ]:
157.36000

Related Compounds