2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone

Names

[ CAS No. ]:
10212-31-4

[ Name ]:
2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone

Biological Activity

[Description]:

2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C10H15N3O5

[ Molecular Weight ]:
257.24

Related Compounds