Influenza virus-IN-1

Names

[ CAS No. ]:
108729-21-1

[ Name ]:
Influenza virus-IN-1

Biological Activity

[Description]:

Influenza virus-IN-1 (compound 14) is a potent influenza A virus inhibitor with an EC50 of 2.46 µM and CC50 of >200 µM. Influenza virus-IN-1 shows a concentration dependent inhibition activity for PAN endonuclease with EC50 of 312.36 nM. Influenza virus-IN-1 shows shows anti-influenza A virus activities[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus
Research Areas >> Inflammation/Immunology

[Target]

EC50: 2.46 µM (influenza virus); CC50: >200 µM (influenza virus)[1]


[References]

[1]. Liao Y, et al. Synthesis and SARs of dopamine derivatives as potential inhibitors of influenza virus PAN endonuclease. Eur J Med Chem. 2020 Mar 1;189:112048.

Chemical & Physical Properties

[ Molecular Formula ]:
C16H17NO5

[ Molecular Weight ]:
303.31

Related Compounds