Antitumor agent-63
Names
[ CAS No. ]:
1627600-90-1
[ Name ]:
Antitumor agent-63
Biological Activity
[Description]:
Antitumor agent-63 (Compound 40), a 20 (S)-O-linked camptothecin (CPT) glycoconjugate, is an antitumor agent without toxicity towards normal cells. Antitumor agent-63 shows high stability and very weak direct topoisomerase I (Topo I) inhibition[1].
[Related Catalog]:
[Target]
Top1
[In Vitro]
Antitumor agent-63 (Compound 40) shows cytotoxicity activities with IC50 values of 1.2, 0.8, 30.5 and >100 µM against HepG2, HCT-116, SW1990 and HEK-293, respectively[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C38H46N4O18
[ Molecular Weight ]:
846.79