N-(3-Methylbutyl)adenosine

Names

[ CAS No. ]:
17659-78-8

[ Name ]:
N-(3-Methylbutyl)adenosine

[Synonym ]:
N6-Isopentyladenosine
Adenosine,N-(3-methylbutyl)
N-(3-Methylbutyl)adenosine
N6-(3-methyl-butyl)-adenosine

Biological Activity

[Description]:

N-(3-Methylbutyl)adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

[2]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

Chemical & Physical Properties

[ Density]:
1.57

[ Boiling Point ]:
632.9ºC at 760mmHg

[ Molecular Formula ]:
C15H23N5O4

[ Molecular Weight ]:
337.37

[ Flash Point ]:
336.5ºC

[ Exact Mass ]:
337.17500

[ PSA ]:
125.55000

[ Vapour Pressure ]:
6.93E-17mmHg at 25°C

[ Index of Refraction ]:
1.708

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream