2’-O,4’-C-Methyleneuridine

Names

[ CAS No. ]:
200435-92-3

[ Name ]:
2’-O,4’-C-Methyleneuridine

[Synonym ]:
2-(5''-Phosphoribosyl)-5'-amp
(1S,3R,4R,7S)-7-hydroxy-1-hydroxymethyl-2,5-dioxabicyclo[2.2.1]heptane uracil
Ado(P)-Rib-P
(1S,3R,4R,7S)-7-hydroxy-1-hydroxymethyl-3-(uracil-1-yl)-2,5-dioxabicyclo[2.2.1]heptane
Ribosyladenosine 5',5''-bis(phosphate)
2'-(5-phosphoribosyl)adenosine 5'-monophosphate
2'-O,4'-C-methyleneuridine
2'-(5''-Phosphoribosyl)-5'-adenosine monophosphate

Biological Activity

[Description]:

2’-O,4’-C-Methyleneuridine (Compound 15a) is a bicyclic nucleoside.

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Sharma VK, et al. Chemoenzymatic convergent synthesis of 2'-O,4'-C-methyleneribonucleosides. J Org Chem. 2014 Jul 3;79(13):6336-41.

Chemical & Physical Properties

[ Density]:
1.695g/cm3

[ Molecular Formula ]:
C₁₀H₁₂N₂O₆

[ Molecular Weight ]:
256.21200

[ Exact Mass ]:
256.07000

[ PSA ]:
114.04000

[ Storage condition ]:
2-8℃

2’-O,4’-C-Methyleneuridine

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds