PPARγ agonist 3

Names

[ CAS No. ]:
2011801-48-0

[ Name ]:
PPARγ agonist 3

Biological Activity

[Description]:

PPARγ agonist 3 (Compound 18a) is a potent and selective agonist of PPARγ. PPARγ agonist 3 is not cytotoxic neither on non-resistant nor on resistant cells. PPARγ agonist 3 exerts antitumor potency only in combination with Imatinib[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR

[References]

[1]. Schoepf AM, et al. Overcoming imatinib resistance in chronic myelogenous leukemia cells using non-cytotoxic cell death modulators. Eur J Med Chem. 2020 Jan 1;185:111748.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H23N3O

[ Molecular Weight ]:
369.46

Related Compounds