Antifungal agent 31

Antifungal agent 31 (compound 12) is a potent and orally active triazole antifungal agents with a pyrrolotriazinone scaffold. Antifungal agent 31 shows antifungal activity against Candida spp. and filamentous fungi. Antifungal agent 31 significantly reduced mortality rates and kidney fungal burden in two murine models of lethal systemic infections[1].

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

[1]. Montoir D, et al. New azole antifungals with a fused triazinone scaffold. Eur J Med Chem. 2020 Mar 1;189:112082.