Influenza virus-IN-2

Names

[ CAS No. ]:
2411584-06-8

[ Name ]:
Influenza virus-IN-2

Biological Activity

[Description]:

Influenza virus-IN-2 (compound 19) is a potent influenza virus inhibitor with an EC50 of 2.58 µM and CC50 of 150.85 µM. Influenza virus-IN-2 shows a concentration dependent inhibition activity for PAN endonuclease with EC50 of 489.39 nM. Influenza virus-IN-2 shows shows anti-influenza A virus activities[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus
Research Areas >> Inflammation/Immunology

[Target]

EC50: 2.58 µM (influenza virus); CC50: 150.85 µM (influenza virus)[1]


[References]

[1]. Liao Y, et al. Synthesis and SARs of dopamine derivatives as potential inhibitors of influenza virus PAN endonuclease. Eur J Med Chem. 2020 Mar 1;189:112048.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H17NO5

[ Molecular Weight ]:
315.32

Related Compounds