HDAC6/8/BRPF1-IN-1
Names
[ CAS No. ]:
2484255-65-2
[ Name ]:
HDAC6/8/BRPF1-IN-1
Biological Activity
[Description]:
HDAC6/8/BRPF1-IN-1 is a dual inhibitor of both HDAC6/8 and the bromodomain and PHD finger containing protein 1 (BRPF1). HDAC6/8/BRPF1-IN-1 has inhibitory activity for HDAC1, HDAC6 and HDAC8 with IC50 values of 797 nM, 344 nM and 908 nM, respectively. HDAC6/8/BRPF1-IN-1 has inhibitory activity for BRPF1 with an Kd value of 175.2 nM. HDAC6/8/BRPF1-IN-1 can be used for the research of cancer[1].
[Related Catalog]:
[Target]
HDAC1:797 nM (IC50)
HDAC6:344 nM (IC50)
HDAC8:908 nM (IC50)
[In Vitro]
HDAC6/8/BRPF1-IN-1 has inhibitory activity for HDAC1, HDAC6 and HDAC8 with IC50 values of 797 nM, 344 nM and 908 nM, respectively[1]. HDAC6/8/BRPF1-IN-1 has inhibitory activity for BRPF1 with an Kd value of 175.2 nM[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C18H17N3O5S
[ Molecular Weight ]:
387.41