DNA Gyrase-IN-3

Names

[ CAS No. ]:
2522667-08-7

[ Name ]:
DNA Gyrase-IN-3

Biological Activity

[Description]:

DNA Gyrase-IN-3 (Compound 28) is a bacterial DNA gyrase B inhibitor with IC50s of 5.41-15.64 µM for E. coli DNA gyrase. Anti-tubercular and antibacterial activity[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Mohamed A Omar, et al. Novel anti-tubercular and antibacterial based benzosuberone-thiazole moieties: Synthesis, molecular docking analysis, DNA gyrase supercoiling and ATPase activity. Bioorg Chem. 2020 Nov;104:104316.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H20N6OS2

[ Molecular Weight ]:
400.52

Related Compounds