DNA-PK-IN-1

Names

[ CAS No. ]:
2663850-40-4

[ Name ]:
DNA-PK-IN-1

Biological Activity

[Description]:

DNA-PK-IN-1 is a potent inhibitor of DNA-PK. DNA-dependent protein kinase (DNA-PK) is a DNA-PK enzyme complex composed of Ku70/Ku80 heterodimer and DNA-dependent protein kinase catalytic subunit (DNA-PKcs). DNA-PK-IN-1 has the potential for the research of cancer diseases (extracted from patent WO2021136463A1, compound 1)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> DNA-PK
Signaling Pathways >> PI3K/Akt/mTOR >> DNA-PK

[References]

[1]. Yonggang Wei, et al. Purine derivatives and their use in medicine. Patent WO2021136463A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H26N8O2

[ Molecular Weight ]:
446.50

Related Compounds