NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT

Names

[ CAS No. ]:
2857037-69-3

[ Name ]:
NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT

Biological Activity

[Description]:

NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (compound I) is a topoisomerase I inhibitor, which can be delivered to cells through conjugated antibody targeting, and has good ADC activity in vivo and in vitro[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin

[References]

[1]. Andrew C. Phillips, et al. Anti-c-met antibody drug conjugates.WO2022232834.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H23N3O6

[ Molecular Weight ]:
473.48

Related Compounds