Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT

Names

[ CAS No. ]:
2857037-70-6

[ Name ]:
Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT

Biological Activity

[Description]:

Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (Formula V) is a drug-linker conjugate that composed of a potent topoisomerase I inhibitor and a linker to make antibody drug conjugate (ADC)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase

[Target]

Drug-Linker Conjugates for ADC[1]


[In Vitro]

Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT 可以与抗 c-Met 抗体偶联形成抗 c-Met 拓扑异构酶 1 抑制剂抗体药物偶联物 (ADC)。

[References]

[1]. Phillips AC, et, al. Anti-c-met antibody drug conjugates. WO2022232834A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C36H38BrN5O9

[ Molecular Weight ]:
764.62

Related Compounds