Antituberculosis agent-8

Names

[ CAS No. ]:
2874263-74-6

[ Name ]:
Antituberculosis agent-8

Biological Activity

[Description]:

Antituberculosis agent-8 (Compound 9i) is an antitubercular agent with an MIC of 3.53 μM (1.6 μg/mL) against M. tuberculosis H37Rv. Antituberculosis agent-8 also shows good antifungal activity against A. niger with an MIC of 62.50 μM[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal
Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Antituberculosis agent-8 (Compound 9i) shows antimicrobial activity with MICs of 3.53, 62.50, 125, 250 and 250 μM against M. tuberculosis H37Rv, A. Niger, C. albicans, S. albus, B. subtilis, respectively[1].

[References]

[1]. Shinde A, et al. Synthesis, Characterization, and Antimicrobial Activity Screening of Some Novel 3-(2-(3-(Substituted benzyloxy)oxetan-3-yl)-3-fluorophenoxy)-8-fluoro-2-methylquinoline Derivatives as Potential Antimycobacterial Agents. ACS Omega. 2022 Dec 6;7(50):47096-47107.  

Chemical & Physical Properties

[ Molecular Formula ]:
C25H19F3N2O3

[ Molecular Weight ]:
452.43

Related Compounds