SIRT5 inhibitor 2

Names

[ CAS No. ]:
340306-87-8

[ Name ]:
SIRT5 inhibitor 2

Biological Activity

[Description]:

SIRT5 inhibitor 2 (compound 49) is a potent SIRT5 inhibitor with an IC50 value of 2.3 μM. SIRT5 inhibitor 2 has inhibitory activity against the SIRT5-dependent desuccinylation. SIRT5 inhibitor 2 can be used for researching cancer and neurodegenerative diseases[1].

[Related Catalog]:

Signaling Pathways >> Epigenetics >> Sirtuin
Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin
Research Areas >> Neurological Disease

[Target]

SIRT5:2.3 μM (IC50)


[References]

[1]. Wang Y, et al. Overview of SIRT5 as a potential therapeutic target: Structure, function and inhibitors. Eur J Med Chem. 2022;236:114363.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H12Cl2N2O3S

[ Molecular Weight ]:
407.27

Related Compounds