Alpha-inosine

Names

[ CAS No. ]:
38183-47-0

[ Name ]:
Alpha-inosine

[Synonym ]:
9-α-D-Ribofuranosylhypoxanthin
9-α-D-ribofuranosyl-1,9-dihydro-purin-6-one
α-Inosin
9-((2S,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one

Biological Activity

[Description]:

Alpha-inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C10H12N4O5

[ Molecular Weight ]:
268.23

[ Exact Mass ]:
268.08100

[ PSA ]:
133.49000

Related Compounds