L-Tyrosine β-naphthylamide

Names

[ CAS No. ]:
4357-95-3

[ Name ]:
L-Tyrosine β-naphthylamide

[Synonym ]:
Einecs 224-432-6
H-Tyr-bNA
TYROSINE-BETANA
L-tyrosine B-naphthylamide
L-Tyrosine--naphthylamide

Biological Activity

[Description]:

L-Tyrosine β-naphthylamide is a tyrosine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.296g/cm3

[ Boiling Point ]:
610.3ºC at 760mmHg

[ Molecular Formula ]:
C₁₉H₁₈N₂O₂

[ Molecular Weight ]:
306.35800

[ Flash Point ]:
322.9ºC

[ Exact Mass ]:
306.13700

[ PSA ]:
75.35000

[ LogP ]:
3.82720

[ Index of Refraction ]:
1.715

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H351

[ Precautionary Statements ]:
P281

[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
40

[ Safety Phrases ]:
22-36

[ RIDADR ]:
NONH for all modes of transport

Articles

L-Tyrosine beta-naphthylamide is a potent competitive inhibitor of tyramine N-(hydroxycinnamoyl)transferase in vitro.

Phytochemistry 56 , 523-527, (2001)

L-Tyrosine beta-naphthylamide, a synthetic substrate designed to measure tyrosine aminopeptidase activity, is a potent inhibitor of hydroxycinnamoyl-CoA:tyramine N-(hydroxycinnamoyl)transferase (THT) ...

Membrane-bound tyrosine aminopeptidase activities in the rat brain throughout the estrous cycle.

Life Sci. 59 , 1097-1101, (1996)

Puromycin sensitive and insensitive membrane-bound aminopeptidase activity levels during the estrous cycle in several brain areas have been described in this research. We have found the highest aminop...

Effect of lithium treatments on the tyrosine-aminopeptidase activities in the rat brain and the pituitary gland.

Arzneimittelforschung 49 , 816-819, (1999)

Lithium (CAS 7439-93-2) is being utilized widely for the treatment of manic-depressive illness. However, the neurochemical mechanism of the ion action still remains relatively obscure. In the present ...